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Dermatological and Cosmeceutical Development: Absorption Efficacy and Toxicity


Publication Date   August 2007
Publisher   Informa Healthcare
Product Type   Book
Pages   600
ISBN Number   978-0-8493-7589-7
Product Code   IFH074
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Price £130.00

approximately: $230 | €165

Summary


Edited by Kenneth A. Walters, An-eX Analytical Services Ltd., Cardiff, UK and Michael S. Roberts, Westlake, Australia Recent advances in our understanding of the development and morphology of normal skin have led to improved methods to deliver therapeutic compounds to selected targeted areas both within the skin and systemically.

This reference provides a clear overview of current pharmaceutical and cosmeceutical practices in the management of both major and minor skin disorders and provides an expansive overview of novel drugs and therapies used to treat these conditions.

Content


  • Introduction
    • Skin Structure, Pharmaceutics, Cosmeceutics and Efficacy of Topically Applied Agents
  • Specific Factors Affecting Targeting and Efficacy
    • Broken Bricks, Cracked Mortar or Something Deeper
    • Skin Disorders and Recent Therapies
    • Effective Targeting of Topical and Deeper Sites
    • Variability in Skin Barrier Properties Site, Age and Racial Variability
    • Permeability through Diseased and Damaged Skin
    • Effective Systemic Delivery by Transdermal Drug Delivery Systems
    • Targeting The Appendages
    • Drug Delivery to and through The Nail- Differences with Respect to The Stratum Corneum
  • Pharmaceutical Therapy
    • Treatment of Dermatitis
    • Drugs for Pain and Inflammation
    • Novel Topically Active Anti-Inflammatory and Anti-Microbial Compounds
    • Advances in Treatment of Psoriasis and Other Autoimmune Disorders
    • Codrug Therapy for Dermatological Diseases
    • Topical Therapeutic Agents Used in Wound Care
    • Treatment of Burns
  • Cosmeceutical Therapy
    • Principles of Cosmeceuticals
    • Evolution of Cosmeceutics and Its Application to Skin Disorders Including Ageing and Blemishes
    • Evidence Based Cosmeceutical Therapy
    • Natural Ingredients Used in Cosmeceuticals
    • Formulation Strategies for Cosmeceuticals
    • Hydroxyacids, Retinoids and Depigmentation Agents
    • Moisturizers
    • Absorption, Evaporation and Efficacy of Insect Repellents, Essential Oils and Other Cosmeceuticals on Human Skin
    • Efficacy and Safety of Tea Tree and Other Oils
    • Skin Toxicity and Absorption of Natural Cosmetic Ingredients
    • Contact Allergy to Cosmeceuticals
    • Percutaneous Absorption of Sunscreens
    • Effective Cosmeceutical Strategies for Minimising Sun Damage, Skin Ageing and Blemishes
    • Getting The Balance Right in Using Sunscreen and Tanning Agents Implications in Relation to The Need for Sunlight and Vitamin D in Bone Health and Prevention of Autoimmune Diseases, Cancers, and Cardiovascular Disease
    • Percutaneous Absorption of Hairdyes
    • Safety Assessments Based on Exposure, Penetration and Toxicity Considerations
  • Improving Therapeutic Outcomes
    • Getting The Dose Right in Dermatological Therapy
    • Chemical Penetration Enhancement Possibilities and Problems
    • Structure/Transport of Enhancers
    • Metered Dose