Targeted Therapies in Oncology

Summary

Targeted therapy is one of the most burgeoning areas of development in cancer research. Increasing knowledge in tumor formation and growth at the molecular level has generated a broad array of therapeutic options, including signal transduction inhibition, antiangiogenic and anti-vascular agents, cell cycle inhibitors, telomerase and telomere interacting agents, apoptosis inducers, and anti-invasive agents. This book presents an authoritative overview of existing molecular targeted therapies, their relevance and role for specific tumors, and their clinical efficacy and impact on patient treatment.

Contents

• Overview of Existing Therapies
• Signal Transduction Inhibitors
• Cell Cycle Inhibitors
• Apoptosis Modulators
• Anti- Angiogenic Agents
• Antivascular Agents
• Anti-Invasive Agents
• Telomerase and Telomere Interacting Agents
• Targeted Agents at Transversal Mechanisms
• Conclusion