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Commercial Insight: Antipsychotics

From Blockbuster Brands to Billion Dollar Generics

Publication Date   December 2004
Publisher   Datamonitor
Product Type   Strategic Report
Pages   173
ISBN Number   not applicable
Product Code   DAT272
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Price £8,000.00

approximately: $15,844 | €10,169

Summary


Second Generation Antipsychotics (SGAs) continue to drive the antipsychotic market with a growth rate of 27.2% between 2002-2003, yielding revenues of over $9.5 billion in 2003 responsible for a 93.3% share of the market. However, several patent expiries and product launches are set to send the market through a period of change.

With an increasingly crowded schizophrenia market, SGA manufacturers are seeking to add new indications to their product's labeling, capitalizing on the existing high off-label. Already, the majority of SGAs are approved for bipolar mania, and many have or are in the process of gaining approval for bipolar maintenance, as well as other niche areas.

Zyprexa, the market leading SGA, is currently experiencing patent challenges from numerous generics manufacturers. Datamonitor believes it is likely that Lilly will prevail in the courts, although, if generic incursion occurs in 2005, the SGA market could look very different.

The extreme interest in this market place by generics manufacturers is unsurprising. The SGA market currently includes three blockbuster brands with Abilify joining this select club in 2005. Datamonitor forecasts that three of the generic molecules will see blockbuster revenues by 2013.

This Report Includes:

  • Overview of current market including profiles of key brands and key events impacting each brand during 2003-2004h3>
  • Assessment of current and future opportunities and threats in the antipsychotics market across the seven major pharmaceutical markets
  • Global sales for leading antipsychotic products from 1999-2003 are presented, with projections for future performance up to 2014h3>
  • In-depth discussion of assumptions and events used in forecast analysis

Content


  • Chapter 1 Executive Summary
    • Objective of the analysis
    • Datamonitor insight into the antipsychotics market
  • Chapter 2 Market Definition And Overview
    • Market definition for this report
    • Current market situation
    • Zyprexa - the gold-standard antipsychotic
    • Strategic scoping and focus
  • Chapter 3 Country Market Assessments
    • Current and future opportunities and threats in the antipsychotic market
    • Global opportunities and threats
    • Opportunities
    • Threats
    • US
    • Market overview
    • Opportunity
    • Threats
    • Japan
    • Opportunities
    • Threats
    • France
    • Market overview
    • Opportunity
    • Threats
    • Germany
    • Market overview
    • Opportunities
    • Threats
    • Italy
    • Market overview
    • Opportunities
    • Threats
    • Spain
    • Market overview
    • Opportunities
    • Threats
    • UK
    • Market overview
    • Opportunities
    • Threats
  • Chapter 4 Forecast Analysis
    • Assumptions and events
    • 2004
    • Genericization of Solian
    • Launch of IM Zyprexa
    • Zyprexa approval for bipolar disorders
    • Risperdal receives approvable letter for autism
    • Risperdal approval for bipolar disorders
    • Risperdal Consta launch
    • Seroquel approval for bipolar mania
    • Geodon approved for bipolar mania
    • Abilify launch in the EU and FDA approval for bipolar mania in the US
    • Poor 2004 performance for Zyprexa
    • 2005
    • Re-launch of Serdolect
    • Launch of Seroquel in France
    • Abilify lifecycle management
    • 2006
    • Launch of Asenapine
    • Launch of paliperidone ER
    • Serdolect patent expiry
    • 2007
    • Zomaril launch
    • Geodon US patent expiry
    • Seroquel patent expiry
    • Launch of Bifeprunox
    • 2008
    • Seroquel line extension
    • Risperdal patent expiry
    • Launch of ORG-24448
    • Launch of PNU170413
    • 2009
    • Launch of blonanserin
    • Abilify global patent expiry
    • Zomaril patent expiry
    • 2011
    • Seroquel US patent expiry
    • Zyprexa patent expiry
    • Limitations of data
    • Forecasts
  • Chapter 5 Commercial Impact And Lifecycle Management: Case Studies
    • Achieving and maintaining market leadership
    • Different strategies leading to differing definitions of market leader
    • Indication expansion
    • Reformulations
    • Specialization or generalization - Zyprexa versus Risperdal
    • Risperdal lifecycle strategies
    • Zyprexa lifecycle strategies
    • Strategies employed by Zyprexa and Risperdal
    • Lifecycle strategies - the pros, the cons and the implications
    • Choice, implementation and outcome of lifecycle strategies
    • BMS outlines future lifecycle strategies for Abilify
    • Generic threat to Zyprexa
    • Zyprexa patent challenge
    • Anticipation
    • Obviousness
    • Inequitable conduct
    • Double-patenting
    • Public use
    • Trial outcome
    • The worst case scenario - approval of generic olanzapine
    • The impact of generic olanzapine
  • Appendix A
  • Appendix B