Drug Discovery

High-Level Systems Biology Modeling in Drug Development

Publication Date June 2006
Publisher IDC
Product Type Report
Pages 20
ISBN Number not applicable
Product Code IDC049

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Summary

This report examines the state of high-level systems biology modeling adoption within the pharmaceutical industry, the progress and prospects for modeling technology providers, and key applications for high-level modeling throughout drug discovery and development. Access to high-level systems biology modeling enables researchers to interactively leverage accumulated biological knowledge in the form of biological pathways and systems and to rapidly characterize and predict drug effects and identify associated biomarkers.

Content

In This Report

Situation Overview

What Is High-Level Modeling and Simulation?

Key Applications in Drug Discovery

Figure: TNFa Effects in Entelos' Rheumatoid Arthritis PhysioLab Model

Figure: Use of Modeling in Supporting Drug Development at the FDA

Obstacles to Modeling

Future Outlook

Essential Guidance

Learn More

Related Research

Appendix: Representative Vendor Outlook

Entelos

Genstruct

Gene Network Sciences

Optimata

Genomatica

Pharsight

Supporting Cast

Pathway Providers

Basic Tools Providers

Data Generators

Synopsis