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Drug Discovery

DNA Sequencing In Drug Discovery

Market outlook for applications, tools and services, and 40 company profiles

Publication Date January 2010
Publisher Business Insights
Product Type Report
Pages 179
ISBN Number not applicable
Product Code RBI00203

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Summary

The advent of DNA sequencing technology has had a vast impact on the field of drug development. It has played a key role in the success of the Human Genome Project which has made it an essential tool for genetic analysis. Advanced technological developments in microarrays, bioinformatics and similar tools have increased the scope of applications and services.

This report covers regional markets, products and services while evaluating them over the next five years, and profiles almost 40 companies involved in the DNA sequencing market.

Key features of this report:

  • It analyzes the market data ( revenues ) of DNA sequencing tools and services in North America, Europe, Asia and rest of the world that includes Middle East, Africa, Russia, Latin America and Australia.
  • Key market drivers and restraints for the parent segments and evaluation of respective sub segments with respect to market dynamics.
  • Covers microarray, DNA sequencing kits, chromatography, mass spectrometry, DNA amplification and many others within the tools market along with their sub segments. The services market includes high throughput sequencing , shot gun sequencing , re-sequencing, sample process and primer walking, single pass analysis and bacterial identification.

Scope of this report:

  • Understand the emerging technologies and the growth associated for evaluation of potential of the type of products and services.
  • Understanding the product developments on which companies are focusing to evaluate new technological trends.
  • For evaluation of growth prospective for DNA sequencing applications and determining lucrative markets.

Key Market Issues:

  • Funding from public institutes is encouraging market players to focus on the development of the DNA sequencing technology.
  • The withdrawal of certain drugs from the market due to their lack of efficacy among the worldwide patient population has created a need to address variations in diseases and drug responses on an individual basis.
  • Next generation sequencing may hinder the growth of the market for first-generation DNA sequencing technology especially in the drug discovery and development sector.

Key findings from this report:

  • The DNA sequencing market growth is highest in the Asian and North American region, with Europe having the second largest market.
  • North America constitutes the major market share with next-generation sequencing attracting the new participants in the region.
  • The existing market participants are strategically positioning their DNA sequencing technologies by differentiating the specificity of the type of their tools and services.
  • Agilent Technologies, CLC Bio, and Life Technologies Corporation are some of the major DNA sequencing companies engaged in collaborative partnerships in the past couple of years.

Key questions answered:

  • What are the important DNA sequencing markets and their growth over the period 2009-14?
  • What are the major technologies and services that have emerged in different areas such as microarray, PCR, re-sequencing, high throughput sequencing?
  • In which areas are the companies focusing while forming strategic alliances with other market players?
  • What is the current potential of DNA sequencing applications with respect to drug development and discovery?

Contents

  • Table of contents
    • DNA Sequencing in Drug Discovery
    • Executive summary
    • Market overview
    • Market dynamics
    • Global DNA sequencing tools & services market
    • Company profiles
  • Chapter 1 Market overview
    • Summary
    • Evolution of DNA sequencing
    • DNA sequencing and drug discovery
    • Defining the market
    • Need for more reliable and compatible tools
    • High throughput and next-generation sequencing - attractive growth factors
    • DNA sequencing tools dominate the market
    • Protecting DNA sequencing technology
    • Applications of DNA sequencing
    • Drug development
    • Clinical trials
    • Whole genome testing
    • Toxicology prediction
    • Identification of drug resistance
    • Drug discovery
  • Chapter 2 Market dynamics
    • Summary
    • Introduction
    • Regional markets
    • North America
    • Europe
    • Asia
    • RoW
    • Competitive landscape
    • Recent agreements and collaborations
    • Recent launches
    • Market drivers
    • Funding from public institutes
    • NGS technologies
    • Patient profiling for genetic disorders
    • Development of personalized medicine
    • High productivity rates
    • Market restraints
    • Shift in sequencing market trends
    • Introduction of NGS technologies
  • Chapter 3 Global DNA sequencing tools & services market
    • Summary
    • DNA sequencing tools
    • Microarray
    • Biochip microarray
    • Gel array
    • Array design kit
    • Low and high density microarrays
    • Bioinformatics
    • Electrophoresis
    • Gel electrophoresis
    • Capillary electrophoresis
    • DNA sequencing kits
    • Consumables, chemicals, reagents and probes
    • DNA polymerase
    • Primers
    • Automated DNA sequencers
    • Chromatography
    • DNA amplification (PCR)
    • Mass spectrometry
    • Microscopy-based techniques
    • Electron microscopy
    • Atomic force microscopy
    • Microfluidics-enabled workstations
    • Barcode readers for DNA sample presentation
    • Computational chemistry and biology modeling
    • Spotters/arrayers
    • Centrifuge
    • Scanners
    • Thermal cyclers
    • Charge-coupled devices (CCDs)
    • Plates, strips and columns
    • DNA sequencing services
    • High throughput sequencing
    • Shotgun sequencing
    • Re-sequencing
    • Sample process and primer walking
    • Single pass analysis
    • Bacterial identification
    • Market drivers
    • Microarray technology is a powerful tool for high throughput screening
    • Increasing applications of microarrays
    • Increasing applications of bioinformatics in R&D
    • Technological breakthroughs generate need for efficient DNA sequencing
    • Genomics and drug discovery applications of automated sequencers
    • Diagnostic applications of automated sequencers
    • Applications in comparative research projects of automated sequencers
    • Developments in PCR technology
    • PCR is a reliable tool for multiple applications
    • Government initiative for funding
    • Market restraints
    • Limited scope of microarrays for pathogen enumeration
    • Time loss due to large number of laboratory specific variations for microarrays
    • Low cost next-generation technologies hinder growth of microarrays
    • Incompatibility issues of current bioinformatics tools
    • High cost of modifying supporting products
    • High cost and reliability issues of PCR technology
  • Chapter 4 Company profiles
    • Summary
    • 454 Life Sciences
    • Company overview
    • Products and services
    • Company strategy
    • Other events
    • Affymetrix
    • Company overview
    • Product and services
    • Company strategy
    • Agilent Technologies
    • Company overview
    • Products and services
    • Company strategy
    • Beckman Coulter, Inc
    • Company overview
    • Products and services
    • Company strategy
    • Bio-Rad Laboratories
    • Company overview
    • Products and services
    • Company strategy
    • Caliper Life Sciences
    • Company overview
    • Products and services
    • Company strategy
    • CapitalBio Corp
    • Company overview
    • Products and services
    • Company strategy
    • CombiMatrix Corp
    • Company overview
    • Products and services
    • Company strategy
    • Commonwealth Biotechnologies, Inc
    • Company overview
    • Products and services
    • Company strategy
    • Complete Genomics, Inc
    • Company overview
    • Products and services
    • Company strategy
    • DNA Vision
    • Company overview
    • Products and services
    • Company strategy
    • Enzo Biochem, Inc
    • Company overview
    • Products and services
    • Company strategy
    • EPICENTRE Biotechnologies
    • Company overview
    • Products and services
    • Company strategy
    • Eurofins MWG Operon
    • Company overview
    • Products and services
    • Company strategy
    • GE Healthcare
    • Company overview
    • Products and services
    • Company strategy
    • Gen-Probe Life Sciences
    • Company overview
    • Products and services
    • Company strategy
    • GVK Biosciences (GVK BIO)
    • Company overview
    • Products and services
    • Company strategy
    • Helicos BioSciences Corp
    • Company overview
    • Products and services
    • Company strategy
    • Illumina, Inc
    • Company overview
    • Products and services
    • Company strategy
    • Integrated DNA Technologies
    • Company overview
    • Products and services
    • Company strategy
    • Kapa Biosystems, Inc
    • Company overview
    • Products and services
    • Company strategy
    • Life Technologies Corp
    • Company overview
    • Products and services
    • Company strategy
    • Microchip Biotechnologies, Inc
    • Company overview
    • Products and services
    • Company strategy
    • Nanogen, Inc
    • Company overview
    • Products and services
    • Company strategy
    • Ocimum Biosolutions Ltd
    • Company overview
    • Products and services
    • Company strategy
    • Pacific Biosciences
    • Company overview
    • Company strategy
    • PamGene
    • Company overview
    • Products and services
    • Company strategy
    • Promega Corp
    • Company overview
    • Products and services
    • Company strategy
    • QIAGEN
    • Company overview
    • Products and services
    • Company strategy
    • Sequenom
    • Company overview
    • Products and services
    • Company strategy
    • Shimadzu Biotech
    • Company overview
    • Products and services
    • Company strategy
    • Siemens Healthcare Diagnostics
    • Company overview
    • Products and services
    • Company strategy
    • Sigma-Aldrich
    • Company overview
    • Products and services
    • Company strategy
    • SoftGenetics, LLC
    • Company overview
    • Products and services
    • Company strategy
    • Thermo Fisher Scientific, Inc
    • Company overview
    • Products and services
    • Company strategy
    • Third Wave Technologies, Inc
    • Company overview
    • Products and services
    • Company strategy
    • VisiGen Biotechnologies
    • Company overview
    • Products and services
    • Company strategy
    • ZS Genetics
    • Company overview
    • Products and services
    • Company strategy
  • Chapter 5 Appendix
    • Glossary
    • Patents
  • List of Figures
    • Figure 1.1: Developments in DNA sequencing
    • Figure 1.2: DNA sequencing in drug discovery and development
    • Figure 1.3: DNA sequencing and drug discovery market
    • Figure 1.4: Relative importance of features of DNA sequencing tools, 2009 versus 2014
    • Figure 1.5: DNA sequencing market drivers
    • Figure 1.6: DNA sequencing tools market dynamics
    • Figure 1.7: Patent analysis by technology, 2007 versus 2009
    • Figure 1.8: Patent analysis by geography, 2006 versus 2008
    • Figure 1.9: Patent applications (%) by competitors, 2004- Oct 09
    • Figure 2.10: Major segments of the global DNA sequencing market (%), 2008-09
    • Figure 2.11: Competitive landscape (%), 2008-09
  • List of Tables
    • Table 1.1: Global DNA sequencing market by tools and services ($m), 2007-14
    • Table 1.2: Global DNA sequencing applications market by applications ($m), 2007-14
    • Table 1.3: Global drug development market, by applications ($m), 2007-14
    • Table 1.4: Global drug discovery market, by applications ($m), 2007-14
    • Table 2.5: Global DNA sequencing market, by geography ($m), 2007-14
    • Table 2.6: Agreements and collaborations in the DNA sequencing market, 2008-09
    • Table 2.7: New product, technology & service launch in the DNA sequencing market, 2008-09
    • Table 2.8: New product, technology & service launch in the DNA sequencing market, 2008-09 (ctd1)
    • Table 2.9: New product, technology & service launch in the DNA sequencing market, 2008-09 (ctd2)
    • Table 2.10: New product, technology & service launch in the DNA sequencing market, 2008-09 (ctd3)
    • Table 3.11: Global DNA sequencing tools market, by geography ($m), 2007-14
    • Table 3.12: Global DNA sequencing tools market, by products ($m), 2007-14
    • Table 3.13: Global microarray market, by products ($m), 2007-14
    • Table 3.14: Global microarray market, by geography ($m), 2007-14
    • Table 3.15: Global biochip microarray market, by geography ($m), 2007-14
    • Table 3.16: Global gel array market, by geography ($m), 2007-14
    • Table 3.17: Global array design kit market, by geography ($m), 2007-14
    • Table 3.18: Global high and low density microarray market, by geography ($m), 2007-14
    • Table 3.19: Global bioinformatics market, by products ($m), 2007-14
    • Table 3.20: Global bioinformatics market, by geography ($m), 2007-14
    • Table 3.21: Global electrophoresis market, by products ($m), 2007-14
    • Table 3.22: Global electrophoresis market, by geography ($m), 2007-14
    • Table 3.23: Global gel electrophoresis market, by geography ($m), 2007-14
    • Table 3.24: Global capillary electrophoresis market, by geography ($m), 2007-14
    • Table 3.25: Global DNA sequencing kits and others market, by geography ($m), 2007-14
    • Table 3.26: Global consumables, chemicals, reagents and probes market, by products ($m), 2007-14
    • Table 3.27: Global consumables, chemicals, reagents and probes market, by geography ($m), 2007-14
    • Table 3.28: Global DNA polymerase market, by geography ($m), 2007-14
    • Table 3.29: Global primers market, by geography ($m), 2007-14
    • Table 3.30: Global automated DNA sequencers market, by geography ($m), 2007-14
    • Table 3.31: Global chromatography market, by geography ($m), 2007-14
    • Table 3.32: Global DNA amplification (PCR) market, by geography ($m), 2007-14
    • Table 3.33: Global mass spectrometry market, by geography ($m), 2007-14
    • Table 3.34: Global microscopy-based techniques market, by products ($m), 2007-14
    • Table 3.35: Global microscopy-based techniques market, by geography, ($m), 2007-14
    • Table 3.36: Global electron microscopy market, by geography ($m), 2007-14
    • Table 3.37: Global AFM market, by geography ($m), 2007-14
    • Table 3.38: Global microfluidics-enabled workstations market, by geography ($m), 2007-14
    • Table 3.39: Global barcode readers market for DNA sample presentation, by geography ($m), 2007-14
    • Table 3.40: Global computational chemistry and biology modeling market, by geography ($m), 2007-14
    • Table 3.41: Global spotters/arrayers market, by geography ($m), 2007-14
    • Table 3.42: Global centrifuge market, by geography ($m), 2007-14
    • Table 3.43: Global scanners market, by geography ($m), 2007-14
    • Table 3.44: Global thermal cycler market, by geography ($m), 2007-14
    • Table 3.45: Global charge-coupled devices market, by geography ($m), 2007-14
    • Table 3.46: Global plates, strips and columns market by geography ($m), 2007-14
    • Table 3.47: Global DNA sequencing services market by products ($m), 2007-14
    • Table 3.48: Global DNA sequencing services market, by geography ($m), 2007-14
    • Table 3.49: Global high throughput sequencing market, by geography ($m), 2007-14
    • Table 3.50: Global shotgun sequencing market, by geography ($m), 2007-14
    • Table 3.51: Global re-sequencing market, by geography ($m), 2007-14
    • Table 3.52: Global sample process and primer walking market by geography ($m), 2007-14
    • Table 3.53: Global single pass analysis market, by geography ($m), 2007-14
    • Table 3.54: Global bacterial identification market, by geography ($m), 2007-14
    • Table 5.55: US patents
    • Table 5.56: US patents (ctd 1)
    • Table 5.57: US patents (ctd 2)
    • Table 5.58: US patents (ctd 3)
    • Table 5.59: US patents (ctd 4)
    • Table 5.60: US patents (ctd 5)
    • Table 5.61: US patents (ctd 6)
    • Table 5.62: US patents (ctd 7)
    • Table 5.63: US patents (ctd 8)
    • Table 5.64: European patents
    • Table 5.65: European patents (ctd 1)
    • Table 5.66: European patents (ctd 2)
    • Table 5.67: European patents (ctd 3)
    • Table 5.68: European patents (ctd 4)
    • Table 5.69: European patents (ctd 5)
    • Table 5.70: European patents (ctd 6)
    • Table 5.71: European patents (ctd 7)
    • Table 5.72: European patents (ctd 7)
    • Table 5.73: European patents (ctd 8)
    • Table 5.74: European patents (ctd 9)
    • Table 5.75: European patents (ctd 10)
    • Table 5.76: European patents (ctd 11)
    • Table 5.77: Japanese patents
    • Table 5.78: Japanese patents (ctd 2)
    • Table 5.79: Japanese patents (ctd 3)
    • Table 5.80: Japanese patents (ctd 4)