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Drug Discovery


Cancer Vaccines Fantasy or Future?


Publication Date   February 2005
Publisher   Bioseeker
Product Type   Report
Pages   not applicable
ISBN Number   not applicable
Product Code   BSK027
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Price £1,635.00

approximately: $2,438 | €1,948

Summary


The concept of utilizing the immune system for the treatment of cancer has been tried for some time without any direct breakthrough success. So far "passive" immunotherapy has experienced most success, with antibody and cytokine therapy leading the way.

An example of difficulties and risks associated with this field is shown by Dendreon's latest failure, in January 2005 of their late stage cancer vaccine candidate Provenge. The new and updated progress analysis report "Cancer Vaccines Fantasy or Future" by BioSeeker Group continues to provide the latest information and analysis on industry related as well as important academic activities.

Active immunotherapy strategies have emerged and progress in the molecular characterization of human tumors and a better understanding of tumor immunology has resulted in the discovery of tumor-associated antigens (TAAs). TAA-based vaccines are at present being evaluated. It is broadly admitted that therapeutic vaccines will initially and in the near future be efficient only on a limited tumor burden. Cancer vaccines ought to be used in an adjuvant setting, for instance in order to remove residual disease after surgical treatment of the tumor. As well, in light of the fact that some of these experimental vaccines can elicit immune and clinical responses even in patients with advanced cancer, cancer vaccines can also be considered for slowing down disease progression and conserve quality of life.

BioSeeker Group has since several years continuously studied the progress in cancer immunotherapy strategies. In this newly updated progress analysis we not only provide a solid background and information structure, we also bring the latest within cancer vaccine achievements.

Reasons Why You Should Read This Report:

  • Get a solid background of what is happening in the Cancer Vaccine field.
  • Learn how the strategies have improved.
  • Make sure that you have the latest information about the most prominent Cancer Vaccine candidates.
  • Speed up your R&D by finding collaborators or partners.

Content


  • Executive Summary
  • Table of contents
  • Bsg General Working Model & Methodology
  • Introduction to Cancer Immunotherapy
  • Cancer immunotherapy strategies.
  • Improved Strategies
  • Progress Analysis
  • Waiting For A Partner, Part I
  • Waiting For A Partner, Part II
  • Limited Success for Anti-Idiotype Antibodies
  • No Light Upon the Gangliosides
  • An immunogenic formulation one step closer to commercialization
  • A Whole Cell Melanoma Vaccine for 2006
  • Uncertainty of Developmental Commitment, Part I
  • Uncertainty of Developmental Commitment, Part II
  • Manufacturing Big Issues
  • Dsmb Recommended Trial Continuation
  • Several Cancer Indications
  • Aims to Apply for FDA and EMEA Approval
  • Without a Trace
  • Next Step?
  • Towards Approval and Market
  • There and Back Again
  • Successful - Money and Honey in the Air
  • Company Profiles
  • Appendix I.
  • Progress Profile Allovoctin-7
  • Progress Profile Avicine
  • Progress Profile BEC2
  • Progress Profile Canvaxin
  • Progress Profile CeaVac
  • Progress Profile DCVax
  • Progress Profile Gastrimmune
  • Progress Profile GMK
  • Progress Profile Lymphocide
  • Progress Profile Melacine
  • Progress Profile M-Vax
  • Progress Profile MyVax
  • Progress Profile Oncophage
  • Progress Profile OncoVax
  • Progress Profile Osidem
  • Progress Profile Ovarex
  • Progress Profile Provenge
  • Progress Profile Theratope
  • Progress Profile TroVax
  • Disclaimer
  • Liability