1: Introduction and Scope of Report
2: Novel Formulations of Top-Selling Non-Biological (Small-Molecule) Drugs
3: Peptides
Rationale for Developing Peptides as Drugs
Peptides in Clinical Trials
Peptides in Pre-clinical Research and Development
4: Polypeptides and Proteins
Human Growth Hormone (hGH)
Insulin
Inhaled Insulin
Other Formulations of Insulin
Proteins
Erythropoietin
Factor VIII
G-CSF (Growth Colony Stimulating Factor)
Interferon Alfa
Interferon Beta
Interleukin-2 (IL-2)
Miscellaneous Proteins
Miscellaneous Proteins and Polypeptides in Research and Development
Companies Specialising in Delivery of Peptides and Proteins
5: Oligonucleotides
Table 2.1 Novel Formulations of Selected Pharmaceuticals in Development
Table 3.1 Peptides on the Market as Therapeutic Agents
Table 3.2 Peptides in Clinical Trials
Table 3.3 Indications of Peptides in Clinical Trials
Table 3.4 Peptides in Pre-clinical Research and Development
Table 4.1 Sales of Growth Hormone in 2001
Table 4.2 Novel Formulations of Human Growth Hormone in Research and Development
Table 4.3 Insulin Sales by Major Companies in 2001
Table 4.4 Novel Formulations of Insulin in Research and Development
Table 4.5 Selected Proteins, Including 2001 Sales
Table 4.6 New Formulations of Erythropoietin in Research and Development
Table 4.7 Formulations of G(M)CSF in Research and Development
Table 4.8 Formulations of Interferon Alfa in Clinical and Pre-clinical Trials
Table 4.9 Novel Formulations of Interferon Beta in Research and Development
Table 4.10 Miscellaneous Proteins and Polypeptides in Clinical and Pre-clinical Trials
Table 4.11 Companies Specialising in Peptide and Protein Delivery
Table 5.1 Oligonucleotides in Research and Development
Table 5.2 Companies with Technologies for Delivery of Oligonucleotides
Table 6.1 Major Products on the Market Using Pulmonary-delivery Devices
Table 6.2 Products in Research and Development Using Pulmonary Delivery
Table 6.3 Companies Specialising in the Development of Novel Inhalation Devices and Formulation Technology
Table 7.1 Commercial Products Using Nasal-delivery Devices
Table 7.2 New Products in Development Using Nasal-delivery Devices
Table 7.3 Companies with Expertise in Nasal Delivery
Table 8.1 Companies with Specialist Technology for Buccal-delivery Systems
Table 9.1 Novel Products in Research and Development Employing Transdermal- delivery Systems
Table 9.2 Selected Companies Specialising in Transdermal Delivery
Table 10.1 PEGylated Products in Research and Development
Table 10.2 Companies with Expertise in PEGylation
Table 11.1 Companies Developing Liposomal and Lipid-based Formulations
Table 12.1 Companies Specialising in Oral Formulation Technology
Table 13.1 Companies Specialising in Parenteral Formulation Technology
