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Drug Delivery |
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Lipospheres in Drug Targets and Delivery
Approaches, Methods, and Applications
Publication Date November 1999
Publisher CRC Press
Product Type Book
Pages 184
ISBN Number 0849316928
Product Code CRC094
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Summary
This publication discusses:-
- Discusses innovative methods of delivering bioactive substances to different systems
- Presents lipospheres as a technical solution to problems associated with controlled release of rugs
- Covers lipospheres as carriers for vaccines
- Provides procedures for specific applications and biological systems
Lipophilic drug carriers such as lipospheres and lipid nanoparticles can modify the in vivo distribution of associated substances. They can therefore be used to improve the therapeutic index of drugs by increasing their efficacy and/or reducing their toxicity. If the delivery systems are carefully designed, lipospheres can help to overcome the delivery problems posed by new classes of active molecules, such as peptides, proteins, genes, and oligonucleotides. They may also extend the therapeutic potential of established drugs. With these powerful abilities, lipid-based nano- and microparticulate carriers are becoming an increasingly important weapon in the pharmaceutical arsenal.
Lipospheres in Drug Targets and Delivery: Approaches, Methods, and Applications presents an overview of the most recent applications of lipid-based nano- and microparticulate carriers in the fields of medicine and biotechnology. It includes chapters on preparation, characterization, and delivery of lipospheres; liposphere based vaccines; therapeutic applications to different systems, and suggestions for further research. With numerous illustrations, tables, and photographs, this book describes procedures for specific applications and biological systems and presents lipospheres as a technical solution to various problems associated with the controlled release of biochemicals.
Written for researchers in medicine and life science, pharmaceutics, and biotechnology, this book provides in-depth coverage of an important topic in biochemistry, molecular biology, and drug development.
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Content
Production and Physicochemical Investigations on Solid Lipid Nanoparticles and on Oil-Loaded Solid Lipid Nanoparticles
Production of Liposphere for Bioactive Compound Delivery
Characterization of Solid Lipid Nano- and Micro-particles
Lipospheres as Delivery System for Peptides and Proteins
Lipospheres for Vaccine Delivery
Solid Lipid Nanoparticles (SLN): Interaction with Cells, Cytokine Production and Enzymatic Degradation
Delivery of Lipophilic Compounds with Lipid Nanoparticles - Application in Dermatics and for Transdermal Therapy
Cationic Lipospheres as Delivery Systems for Nucleic Acid Molecules
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