Complete Target Atlas in Oncology Drug Development: From Tumor to Targeted Therapy

Summary

With the emergence of new technologies and an increased understanding of the biological basis for cancer evolution, the molecular changes that distinguish malignant-cells from normal cells are becoming increasingly apparent, offering a growing range of potential drug targets in the form of altered genes, proteins or corrupted pathways. Drug targets are the critical link between drugs and their role in the treatment of medical disorders.

This report, Complete Target Atlas in Oncology Drug Development, is written for you to identify your competition and understand which targeting strategies are at work within the cancer drug development landscape. It allows you to pin-point which competitors drugs' clinical out-come may have bearing on your own drug development and who are developing sequels to successful drugs. This report also helps you to locate white-spots in the competitive landscape, giving you little or no competition. Conversely it may reveal unexpected competition for you.

Complete Target Atlas in Oncology Drug Development is a multi-report made up by nine different and independent target reports covering five different targeted therapies areas and four major tumor types in detail:

Targeted Therapy Strategies in Cancer
Major Tumor Types

• Apoptosis
• Breast Cancer
• Angiogenesis/VDA/VTA
• Colorectal Cancer
• Antibodies
• Melanoma
• Immunomodulators & Vaccines
• Prostate Cancer
• Protein Kinase Inhibitors

Each report subject (click on each subject for detailed information) covers:

Compound strategies based on sub-cellular localization of cancer drug targets
The Cancer Genome Project and cancer drug targets
Expression levels of identified drug targets in selected tumor type
Pathway analysis of cancer drug targets
Target-target interactions among identified cancer targets
Structure-based drug design in s stimulated by available structure data on biological targets
Unique, in-depth, drug target validating profiles, highlighting twelve themes about the drug target, i.e. protein-protein interaction with other cancer drug targets, pursued cancer indications, drugs under development, presence in the Cancer Genome Project etc.

Drug-target interactome

The progression and maturity of cancer targets: New and unique cancer drug targets
Indication specific reports deal with targets by R&D approach in specified cancer types, whereas targeted therapy specific reports deal with targets by cancer indication.
Cancer drug target profiles by investigator

This report is an open landscape of resources to build, fuel, and drive your scientific competitive vehicle for the advancement of cancer drugs. It will assist you in lead commercial analysis and product strategy thinking to build and nurture current and future portfolio of drug candidates and R&D alliances. This report will help you to streamline your analysis of new as well as of established drug targets, when looking for clinical proofs, indication selection, competitive environment etc.

Contents

• Please note that due to the nature of this report, no Table of Contents is available.