Interstitial Cystitis

Summary

Introduction

Interstitial cystitis (IC) is considered a rare disorder and poor understanding of the underlying causes of the disorder have made diagnosis and management difficult. Moreover, this has impacted on the development of effective drugs for this disorderthere are few available treatments for IC and as a result, significant unmet needs exist.

Scope

• Quantitative treatment data from 190 physicians based in US, Japan, France, Germany, Italy, Spain and UK; supported by key opinion leader comments
• Analysis of epidemiology, presentation and referral patterns, diagnostic assessment, and first- to second-line treatments for IC
• Influences on treatment choice and perception of current drug therapies including pentosan polysulfate sodium and the antimuscarinics
• Influences on treatment choice and perception of current drug therapies, unmet needs and future outlook including the R&D drug pipeline

Highlights

• Presentation rates for IC are higher than in other OAB disorders due to the patient experience of pain. However, discord in the terminology and diagnostic criteria for IC confound diagnosis; and as result, the diagnosis of IC tends to be one of exclusion, and as such can take many years to be reached, bringing unnecessary suffering to the patient.
• IC symptoms have a similar terminology to those of Overactive Bladder, but are fundamentally different. Poor understanding of the disorder and limited treatment options means that many physicians have resorted to using antimuscarinics despite their limited proven efficacy in treating the pain.
• Further research into the etiology of IC is the key to finding a truly effective treatment for IC that works. In the meantime, companies wishing to target the IC market should aim to demonstrate the ability of their drug to treat pain in addition to urgency and frequency.

Reasons to Purchase

• Forecast product sales by understanding key aspects of IC epidemiology, diagnosis and treatment
• Gain a better understanding of the challenges facing current and future players in the IC market

Contents

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• Introduction
• Scope of this report
• Research and analysis highlights
• Key reasons to read this report
• Appendix A
  • Research methodology
  • Physician Sample breakdown
  • Urinary Incontinence and Overactive Bladder Insight Study - Physician Questionnaire
  • Section One Overview of Urinary Incontinence and overactive Bladder
  • Epidemiology
  • Presentation
  • Diagnosis
  • Referral pattern
  • Section Two Stress Urinary Incontinence
  • Diagnosis and treatment of SUI
  • Non-pharmacological treatment
  • Pharmacological treatment for SUI
  • Section Three Overactive Bladder With Urge Symptoms and/or Incontinence
  • Diagnosis and treatment of UUI
  • Pharmacological treatment for UUI
  • Diagnosis and treatment of 'dry OAB'
  • Pharmacological treatment for dry OAB
  • Section Four Mixed Stress/Urge Urinary Incontinence
  • Diagnosis and treatment of mixed SUI/UUI
  • Non-pharmacological treatment
  • Pharmacological treatment for mixed SUI/UUI
  • Section Five Interstitial Cystitis
  • Diagnosis and treatment of IC
  • Pharmacological treatment for IC
  • Section Six Drug Profiles
  • Section A: Drug influences on physicians' choice
  • Section B: The general treatment of urinary incontinence and overactive bladder
  • Contributing experts
  • US
  • Japan
  • Europe
• Appendix B
  • About Datamonitor
  • About Datamonitor Healthcare
  • About the CNS analysis team
  • Disclaimer