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Cancer

Competitive Outlook of Cancer Drug Development

The Missing Handbook to New Product Planning and Portfolio Planning

Publication Date August 2009
Publisher Bioseeker
Product Type Report
Pages 767
ISBN Number not applicable
Product Code BSK00228

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£2,195.00
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Summary

This report includes defined and up to date development strategies for 283 lung cancer therapeutic drugs (>317 projects) within the portfolio of 167 investigators, from Ceased to Marketed. In total the report assesses three
different sub-indications of lung cancer (Non-Small Cell Lung Cancer, Small Cell Lung Cancer and Lung Cancer (general). The report is written for you to understand and assess the impact of competitor entry and corresponding
changes to development strategies for your own portfolio products. It serves as an external commercial advocate for pharmaceutical companies' portfolio planning and new product planning by:

  • Providing you with competitive input to the R&D organization to guide development of early product ideas and ensure efforts are aligned with business objectives

  • Assisting you to make informed decisions in selecting lung cancer sub-indications that are known to be appropriate for your drug's properties

  • Analyzing, correlating and integrating valuable data sources in order to provide accurate data for valuation of pipeline, in-licensing and new business opportunities

  • Providing you with commercial analytic support for due diligence on in-licensing and acquisition opportunities

  • Integrating knowledge for you to consider the therapeutic target for the highest therapeutic outcome and return on investment

    This report will also be an important part of creating and implementing a market development plan for any lung cancer therapeutic drugs to ensure that the optimal market conditions exist by the time the product is
    commercialized.
  • Contents

    1 Executive Summary

    2 About Cancer Highlights

    3 Methodologies

    4 Table of Contents
    4.1 List of Figures
    4.2 List of Tables

    5 Introduction
    5.1 The Scope of this Report
    5.2 Definitions
    5.3 Abbreviations

    6 Consider the Therapeutic Target for the Highest Therapeutic Outcome and Return on Investment
    6.1 Drug Repositioning in Oncology
    6.2 Introduction to Lung Cancer Drug Targets
    6.2.1 Carboxy-lyase Activity Targets
    6.2.2 Catalytic ActivityTargets
    6.2.3 Cell Adhesion Molecule Activity Targets
    6.2.4 Chaperone ActivityTargets
    6.2.5 Chemokine Activity Targets
    6.2.6 Complement Activity Targets
    6.2.7 Cysteine-Type Peptidase Activity Targets
    6.2.8 Cytokine Activity Targets
    6.2.9 DNA Binding Targets
    6.2.10 DNA Repair Protein Targets
    6.2.11 DNA Topoisomerase Activity Targets
    6.2.12 DNA-Directed DNA Polymerase Activity Targets
    6.2.13 DNA-methyltransferase Activity Targets
    6.2.14 Extracellular Ligand-Gated Ion Channel Activity Targets
    6.2.15 Extracellular Matrix Structural Constituent Targets
    6.2.16 G-protein Coupled Receptor Activity Targets
    6.2.17 Glutathione Transferase Activity Targets
    6.2.18 Growth Factor Activity Targets
    6.2.19 GTPase Activity Targets
    6.2.20 Hormone activity Targets
    6.2.21 Hydrolase Activity Targets
    6.2.22 Ion channel Activity Targets
    6.2.23 Kinase Activity Targets
    6.2.24 Kinase regulator activity Targets
    6.2.25 Ligase Activity Targets
    6.2.26 Lipase Activity Targets
    6.2.27 Lipid Kinase Activity Targets
    6.2.28 Metallopeptidase Activity Targets
    6.2.29 Molecular Function Unknown Targets
    6.2.30 Motor Activity Targets
    6.2.31 Oxidoreductase Activity Targets
    6.2.32 Peptidase Activity Targets
    6.2.33 Peroxidase Activity Targets
    6.2.34 Phosphoric Diester Hydrolase Activity Targets
    6.2.35 Protein binding Targets
    6.2.36 Protein Serine/Threonine Kinase Activity Targets
    6.2.37 Protein Threonine/Tyrosine Kinase Activity Targets
    6.2.38 Protein Tyrosine/Serine/Threonine Phosphatase Activity Targets
    6.2.39 Protein-Tyrosine Kinase Activity Targets
    6.2.40 Receptor Activity Targets
    6.2.41 Receptor binding Targets
    6.2.42 Receptor Signaling Complex Scaffold Activity Targets
    6.2.43 Receptor Signaling Protein Serine/Threonine Kinase Activity Targets
    6.2.44 RNA Binding Targets
    6.2.45 RNA-Directed DNA Polymerase Activity Targets
    6.2.46 Serine-Type Peptidase Activity Targets
    6.2.47 Structural Constituent of Cytoskeleton Targets
    6.2.48 Transcription Factor Activity Targets
    6.2.49 Transcription Regulator Activity Targets
    6.2.50 Transcription Regulator Activity Targets
    6.2.51 Transferase Activity Targets
    6.2.52 Transmembrane Receptor Activity Targets
    6.2.53 Transmembrane Receptor Protein Tyrosine Kinase Activity Targets
    6.2.54 Transporter Activity Targets
    6.2.55 Ubiquitin-Specific Protease Activity Targets
    6.2.56 Other Targets
    6.3 The Cancer Genome Project and Lung Cancer Targets
    6.3.1 Lung Cancer Targets Present in the Cancer Gene Census and in the Catalogue of Somatic Mutations in Cancer
    6.4 Structure-based Drug Design in Lung Cancer is Stimulated by Available Structure Data on Biological Targets
    6.5 Target-Target Interactions among Identified Lung Cancer Targets
    6.6 The Drug-Target Interactome
    6.7 Protein Expression Levels of Identified Drug Targets of Lung Cancer Drugs
    6.8 Pathway Analysis of Lung Cancer Drug Targets

    7 The Rise of New Products: How Mature, Unique and Clinically Validated are the Drug Target Profiles Identified in the Lung Cancer Pipeline?
    7.1 Terminated Drug Target Profiles in Lung Cancer
    7.2 Pre-Registration to being Marketed: New and Unique Drug Target Profiles in the Lung Cancer Pipeline
    7.3 Phase III Clinical Development: New and Unique Drug Target Profiles in the Lung Cancer Pipeline
    7.4 Phase II Clinical Development: New and Unique Drug Target Profiles the Lung Cancer Pipeline
    7.5 Phase I Clinical Development: New and Unique Drug Target Profiles in the Lung Cancer
    Pipeline
    7.6 Preclinical Development: New and Unique Drug Target Profiles in the Lung Cancer Pipeline
    7.7 Development Profiles of All Lung Cancer Drug Target Profiles

    8 Compound Strategies at Work: Competitive Benchmarking of Lung Cancer Pipeline by Type of Compound
    8.1 Small Molecules
    8.1.1 Background
    8.1.2 Targets in Lung Cancer
    8.2 Peptide/Protein Drugs
    8.2.1 Background
    8.2.2 Targets in Lung Cancer
    8.3 Antibodies and Antibody-like Structures
    8.3.1 Background
    8.3.2 Targets in Lung Cancer
    8.4 Nucleic Acid Therapies
    8.4.1 Background
    8.4.2 Targets in Lung Cancer
    8.5 Gene Therapy
    8.5.1 Background
    8.5.2 Targets in Lung Cancer
    8.6 Drug Delivery and Nanotechnology
    8.6.1 Background
    8.6.2 Targets in Lung Cancer
    8.7 The Competition Through Close Mechanistic Approximation Among Drugs in Lung Cancer
    8.8 Compound Strategies based on Sub-Cellular Localization of Lung Cancer Drug Targets

    9 Selecting a Sub-Indication of Lung Cancer for Drug Development
    9.1 Lung Cancer (general)
    9.1.1 Players and their Compared Pipeline
    9.1.2 Where is the Real Competition?
    9.1.3 How Successful are They in Their Targeting Strategy?
    9.2 Non-Small Cell Lung Cancer
    9.2.1 Players and their Compared Pipeline
    9.2.2 Where is the Real Competition?
    9.2.3 How Successful are They in Their Targeting Strategy?
    9.3 Small Cell Lung Cancer
    9.3.1 Players and their Compared Pipeline
    9.3.2 Where is the Real Competition?
    9.3.3 How Successful are They in Their Targeting Strategy?

    10 Portfolio Planning: Competitive Benchmarking of Lung Cancer Pipeline by Investigator463
    10.1 Abbott
    10.2 Abraxis BioScience
    10.3 Active Biotech
    10.4 Adherex
    10.5 Advantagene
    10.6 AEgera
    10.7 Aeterna Zentaris
    10.8 Agennix
    10.9 Aida Pharmaceuticals
    10.10 Alchemia
    10.11 Alethia Biotherapeutics
    10.12 Allos Therapeutics
    10.13 Amgen
    10.14 Antisense Pharma
    10.15 Antisoma
    10.16 Anza Therapeutics
    10.17 ApopLogic Pharmaceuticals
    10.18 Archer Biosciences
    10.19 Ariad
    10.20 ArQule
    10.21 Array BioPharma
    10.22 Ascenta Therapeutics
    10.23 Astellas
    10.24 AstraZeneca
    10.25 Bayer
    10.26 Biogen Idec
    10.27 Biokine Therapeutics
    10.28 BioNumerik
    10.29 Boehringer Ingelheim
    10.30 Bristol-Myers Squibb
    10.31 BTG
    10.32 CanBas
    10.33 Celator Pharmaceuticals
    10.34 Cell Genesys
    10.35 Cell Therapeutics
    10.36 Celtic Pharma
    10.37 Center of Molecular Immunology
    10.38 Cephalon
    10.39 CG Therapeutics
    10.40 Chemokine Therapeutics
    10.41 Chong Kun Dang
    10.42 Clavis Pharma
    10.43 CLL Pharma
    10.44 Critical Outcome Technologies
    10.45 Cyclacel
    10.46 CytImmune Sciences
    10.47 Cytokinetics
    10.48 Dabur Pharma
    10.49 Daiichi Sankyo
    10.50 Dainippon Sumitomo Pharma
    10.51 Dara Biosciences
    10.52 Dendreon
    10.53 Dong-A
    10.54 Eisai
    10.55 Eli Lilly
    10.56 Endocyte
    10.57 EntreMed
    10.58 EpiCept
    10.59 Exelixis
    10.60 Galapagos
    10.61 Gemin X Pharmaceuticals
    10.62 Genentech
    10.63 Genmab
    10.64 Genta
    10.65 GenVec
    10.66 Genzyme
    10.67 Geron
    10.68 GlaxoSmithKline
    10.69 GlobeImmune
    10.70 GlycoGenesys
    10.71 Hana Biosciences
    10.72 Hoffmann-La Roche
    10.73 Human Genome Sciences
    10.74 Idera Pharmaceuticals
    10.75 ImClone Systems
    10.76 ImmunoCellular Therapeutics
    10.77 Immunocore
    10.78 ImmunoGen
    10.79 Immunomedics
    10.80 Incyte Corporation
    10.81 Infinity Pharmaceuticals
    10.82 Innovive
    10.83 Inovio
    10.84 Introgen Therapeutics
    10.85 Ipsen
    10.86 Isis Pharmaceuticals
    10.87 Jennerex Biotherapeutics
    10.88 Johnson & Johnson
    10.89 Kiadis
    10.90 Kyowa Hakko Kirin
    10.91 Lorus Therapeutics
    10.92 MacroGenics
    10.93 Medarex
    10.94 MediGene
    10.95 Medisyn Technologies
    10.96 Menarini
    10.97 Merck KGaA
    10.98 MethylGene
    10.99 Micromet
    10.100 Mirna Therapeutics
    10.101 MolMed
    10.102 Mologen
    10.103 Nektar Therapeutics
    10.104 NeoPharm
    10.105 Nerviano Medical Sciences
    10.106 Novacea
    10.107 Novartis
    10.108 OncoGenex Pharmaceuticals
    10.109 Oncothyreon
    10.110 OSI Pharmaceuticals
    10.111 OXiGENE
    10.112 PanaGin
    10.113 PBL Therapeutics
    10.114 PDL BioPharma
    10.115 Pfizer
    10.116 Pharmacyclics
    10.117 PharmaGap
    10.118 PharmaMar
    10.119 Pharmexa
    10.120 Pierre Fabre
    10.121 Pro-Pharmaceuticals
    10.122 Progen
    10.123 Protox Therapeutics
    10.124 Receptor BioLogix
    10.125 Regulon
    10.126 RESprotect
    10.127 Samyang
    10.128 Sanofi-Aventis
    10.129 Sareum
    10.130 Schering-Plough
    10.131 Seattle Genetics
    10.132 ShimodaAtlantic Oncology
    10.133 Shire
    10.134 Sigma-Tau
    10.135 Simcere Pharmaceuticals
    10.136 SRI International
    10.137 SuperGen
    10.138 Supratek Pharma
    10.139 Switch Pharma
    10.140 Taiho
    10.141 Takeda
    10.142 Taxolog
    10.143 Tekmira Pharmaceuticals
    10.144 Telik
    10.145 Thallion Pharmaceuticals
    10.146 Therion Biologics
    10.147 Titan Pharmaceuticals
    10.148 Tracon Pharmaceuticals
    10.149 Tragara Pharmaceuticals
    10.150 Transgene
    10.151 Trion Pharma
    10.152 Twinstrand Therapeutics
    10.153 UCB
    10.154 Valeant
    10.155 Vaxon Biotech
    10.156 Vertex Pharmaceuticals
    10.157 Vion Pharmaceuticals
    10.158 ViRexx
    10.159 Voyager Pharmaceutical
    10.160 Wilex
    10.161 Wyeth
    10.162 Xerion
    10.163 Xoma
    10.164 Yakult Honsha
    10.165 YM BioSciences
    10.166 Zivena
    10.167 Non-industrial Organizations
    11 Disclaimer
    12 Drug Index
    13 Company Index

    List of Figures

    Figure 1: Overall Breakdown of the Included Lung Cancer Therapeutic Pipeline by Sub-Indication and Stage of Development
    Figure 2: Visualization of Target-Target Interactions Among Lung Cancer Drug Targets
    Figure 3: The Drug-Protein Interactome of Lung Cancer Drugs -Clusters I
    Figure 4: The Drug-Protein Interactome of Lung Cancer Drugs - Clusters II
    Figure 5: Head-to-Head Targeting Interactome of Lung Cancer Drugs
    Figure 6: Distribution of Compound Types among Lung Cancer Drugs
    Figure 7: Primary Sub-cellular Localization of Drug Targets
    Figure 8: Breakdown of the Lung Cancer (general) Pipeline - Displaying Number of Drugs, Target Profiles and Investigators by Stage of Development
    Figure 9: Compound Strategy Breakdown of the Lung Cancer (general) Pipeline
    Figure 10: Breakdown of the Non-Small Cell Lung Cancer Pipeline - Displaying Number of Drugs, Target Profiles and Investigators by Stage of Development
    Figure 11: Compound Strategy Breakdown of the Non-Small Cell Lung Cancer Pipeline
    Figure 12: Breakdown of the Small Cell Lung Cancer Pipeline - Displaying Number of Drugs, Target Profiles and Investigators by Stage of Development
    Figure 13: Compound Strategy Breakdown of the Small Cell Lung Cancer Pipeline

    List of Tables

    Table 1: Competitive Pressure Force Among Lung Cancer Drugs
    Table 2: Overview of Drug Target Profile Themes
    Table 3: Terminally Ceased Therapeutic Lung Cancer Targets
    Table 4: Drug Targets of Lung Cancer Drugs Present in the Catalogue of Somatic Mutations in Cancer and in the Cancer Gene Census
    Table 5: Identity of Lung Cancer Drug Targets with Available Biological Structures
    Table 6: Number of Target-Target Interactions among Lung Cancer Drug Targets
    Table 7: Drug-Protein Interactome Clusters
    Table 8: Lung Cancer Drug Targets with Available Protein Expression Profiles
    Table 9: Expression Levels of Identified Drug Targets in Lung Cancer Tissue
    Table 10: Pathway Summary
    Table 11: Drug Targets without any Identified Assigned Pathways
    Table 12: Pathway Profile According to BioCarta of Lung Cancer Drug Targets
    Table 13: Pathway Profile According to KEGG of Lung Cancer Drug Targets
    Table 14: Pathway Profile According to NetPath of Lung Cancer Drug Targets
    Table 15: Number of Drug Target Profiles by their Highest Developmental Stage and Uniqueness
    Table 16: Top Competitive Lung Cancer Target Profiles
    Table 17: Terminated Drug Target Strategies in Lung Cancer
    Table 18 New and Unique Lung Cancer Target Strategies in Pre-Registration to Marketed
    Table 19: New and Unique Lung Cancer Target Strategies in Phase III Clinical Development
    Table 20: New and Unique Lung Cancer Target Strategies in Phase II Clinical Development
    Table 21: The Competition Through Close Mechanistic Approximation Between Phase II Lung Cancer Drugs
    Table 22 New and Unique Lung Cancer Target Strategies in Phase I Clinical Development
    Table 23: The Competition Through Close Mechanistic Approximation Between Phase I Lung Cancer Drugs
    Table 24: New and Unique Lung Cancer Target Strategies in Preclinical Development
    Table 25: The Competition Through Close Mechanistic Approximation Between Phase I Lung Cancer Drugs
    Table 26: The Progression, Maturity and Competitive Comparison of Lung Cancer Drug Target Profiles in Development
    Table 27: Overview of Compound Strategy Competition in Lung Cancer
    Table 28:Overview of the Competitive Landscape of Small Molecular Drugs in Lung Cancer
    Table 29: Head-to-Head Target Competition Between Small Molecule Drugs for the Treatment of Lung Cancer
    Table 30: The Competition Through Close Mechanistic Approximation Between Small Molecule Drugs in Lung Cancer
    Table 31: The Progression, Maturity and Competitive Comparison of Target Profiles of Small Molecule Lung Cancer Drugs in Development
    Table 32: Overview of the Competitive Landscape of Peptide Based Drugs in Lung Cancer
    Table 33: The Progression, Maturity and Competitive Comparison of Target Profiles of Peptide Based Lung Cancer Drug in Development
    Table 34:Overview of the Competitive Landscape of Protein Based Drugs in Lung Cancer
    Table 35: The Competition Through Close Mechanistic Approximation Between Protein Based Drugs in Lung Cancer
    Table 36: The Progression, Maturity and Competitive Comparison of Protein Based Lung Cancer Drug Target Profiles in Development
    Table 37:Overview of the Competitive Landscape of Antibody Drugs in Lung Cancer
    Table 38: The Competition Through Close Mechanistic Approximation Between Antibody Drugs in Lung Cancer
    Table 39: The Progression, Maturity and Competitive Comparison of Target Profiles of Antibody Lung Cancer Drugs in Development
    Table 40:Overview of the Competitive Landscape of Nucleic Acid Therapy Drugs in Lung Cancer
    Table 41: The Progression, Maturity and Competitive Comparison of Target Profiles of Nucleic Acid Lung Cancer Drugs in Development
    Table 42: Vectors in Gene Therapy
    Table 43:Overview of the Competitive Landscape of Gene Therapy Drugs in Lung Cancer
    Table 44: The Competition Through Close Mechanistic Approximation Between Gene Therapy Drugs in Lung Cancer
    Table 45: The Progression, Maturity and Competitive Comparison of Target Profiles of Gene Therapy Lung Cancer Drugs in Development
    Table 46:Overview of the Competitive Landscape of Reformulated Drugs in Lung Cancer
    Table 47: The Competition Through Close Mechanistic Approximation Between Reformulated Drugs in Lung Cancer
    Table 48: The Progression, Maturity and Competitive Comparison of Target Profiles of Reformulated Lung
    Cancer Drugs in Development
    Table 49: The Competition Through Close Mechanistic Approximation Among Drugs in Lung Cancer
    Table 50: Compound Strategies based on Sub-Cellular Localization of Lung Cancer Drug Targets
    Table 51: Competitive Summary of Lung Cancer Drugs by Sub-Indication
    Table 52: Players in the Field of Lung Cancer (general) Drug Development and their Compared Pipeline
    Table 53: The Competition Through Close Mechanistic Approximation Between Lung Cancer (general) Drugs
    Table 54: The Progression, Maturity and Competitive Comparison of Drug Target Profiles in Lung Cancer
    (general) Drug Development
    Table 55: Players in the Field of Non-Small Cell Lung Cancer Drug Development and their Compared Pipeline
    Table 56: The Competition Through Close Mechanistic Approximation Between Non-Small Cell Lung Cancer
    Drugs
    Table 57: The Progression, Maturity and Competitive Comparison of Drug Target Profiles in Non-Small Cell Lung
    Cancer Drug Development
    Table 58: Players in the Field of Small Cell Lung Cancer Drug Development and their Compared Pipeline
    Table 59: The Competition Through Close Mechanistic Approximation Between Small Cell Lung Cancer Drugs
    Table 60: The Progression, Maturity and Competitive Comparison of Drug Target Profiles in Small Cell Lung
    Cancer Drug Development
    Table 61: Abbott's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 62: Abraxis BioScience's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 63: Active Biotech's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 64: Adherex's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 65: Advantagene's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 66: AEgera's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 67: Aeterna Zentaris' Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 68: Agennix's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 69: Aida Pharmaceuticals' Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 70: Alchemia's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 71: Alethia Biotherapeutics' Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 72: Allos Therapeutics' Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 73: Amgen's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 74: Antisense Pharma's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 75: Antisoma's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 76: Anza Therapeutics' Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 77: ApopLogic Pharmaceuticals' Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 78: Archer Biosciences' Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 79: Ariad's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 80: ArQule's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 81: Array BioPharma's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 82: Ascenta Therapeutics' Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 83: Astellas' Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 84: AstraZeneca's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 85: Bayer's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 86: Biogen Idec's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 87: Biokine Therapeutics' Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 88: BioNumerik's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 89: Boehringer Ingelheim's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 90: Bristol-Myers Squibb's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 91: BTG's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 92: CanBas' Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 93: Celator Pharmaceuticals' Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 94: Cell Genesys' Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 95: Cell Therapeutics' Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 96: Celtic Pharma's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 97: Center of Molecular Immunology's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 98: Cephalon's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 99: CG Therapeutics' Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 100: Chemokine Therapeutics' Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 101: Chong Kun Dang's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 102: Clavis Pharma's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 103: CLL Pharma's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 104: Critical Outcome Technologies' Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 105: Cyclacel's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 106: CytImmune Sciences' Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 107: Cytokinetics' Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 108: Dabur Pharma's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 109: Daiichi Sankyo's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 110: Dainippon Sumitomo Pharma's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 111: Dara Biosciences' Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 112: Dendreon's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 113: Dong-A's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 114: Eisai's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 115: Eli Lilly's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 116: Endocyte's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 117: EntreMed's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 118: EpiCept's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 119: Exelixis' Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 120: Galapagos' Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 121: Gemin X Pharmaceuticals' Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 122: Genentech's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 123: Genmab's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 124: Genta's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 125: GenVec's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 126: Genzyme's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 127: Geron's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 128: GlaxoSmithKline's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 129: GlobeImmune's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 130: GlycoGenesys' Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 131: Hana Biosciences' Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 132: Hoffmann-La Roche's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 133: Human Genome Sciences' Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 134: Idera Pharmaceuticals' Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 135: ImClone Systems' Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 136: ImmunoCellular Therapeutics' Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 137: Immunocore's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 138: ImmunoGen's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 139: Immunomedics' Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 140: Incyte Corporation's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 141: Infinity Pharmaceuticals' Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 142: Innovive's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 143: Inovio's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 144: Introgen Therapeutics' Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 145: Ipsen's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 146: Isis Pharmaceuticals' Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 147: Jennerex Biotherapeutics' Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 148: Johnson & Johnson's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 149: Kiadis' Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 150: Kyowa Hakko Kirin's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 151: Lorus Therapeutics' Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 152: MacroGenics' Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 153: Medarex's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 154: MediGene's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 155: Medisyn Technologies' Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 156: Menarini's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 157: Merck KGaA's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 158: MethylGene's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 159: Micromet's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 160: Mirna Therapeutics' Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 161: MolMed's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 162: Mologen's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 163: Nektar Therapeutics' Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 164: NeoPharm's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 165: Nerviano Medical Sciences' Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 166: Novacea's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 167: Novartis' Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 168: OncoGenex Pharmaceuticals' Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 169: Oncothyreon's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 170: OSI Pharmaceuticals' Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 171: OXiGENE's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 172: PanaGin's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 173: PBL Therapeutics' Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 174: PDL BioPharma's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 175: Pfizer's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 176: Pharmacyclics' Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 177: PharmaGap's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 178: PharmaMar's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 179: Pharmexa's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 180: Pierre Fabre's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 181: Pro-Pharmaceuticals' Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 182: Progen's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 183: Protox Therapeutics' Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 184: Receptor BioLogix's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 185: Regulon's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 186: RESprotect's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 187: Samyang's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 188: Sanofi-Aventis' Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 189: Sareum's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 190: Schering-Plough's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 191: Seattle Genetics' Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 192: ShimodaAtlantic Oncology's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 193: Shire's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 194: Sigma-Tau's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 195: Simcere Pharmaceuticals' Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 196: SRI International's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 197: SuperGen's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 198: Supratek Pharma's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 199: Switch Pharma's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 200: Taiho's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 201: Takeda's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 202: Taxolog's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 203: Tekmira Pharmaceuticals' Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 204: Telik's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 205: Thallion Pharmaceuticals' Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 206: Therion Biologics' Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 207: Titan Pharmaceuticals' Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 208: Tracon Pharmaceuticals' Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 209: Tragara Pharmaceuticals' Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 210: Transgene's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 211: Trion Pharma's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 212: Twinstrand Therapeutics' Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 213: UCB's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 214: Valeant's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 215: Vaxon Biotech's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 216: Vertex Pharmaceuticals' Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 217: Vion Pharmaceuticals' Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 218: ViRexx's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 219: Voyager Pharmaceutical's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 220: Wilex's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 221: Wyeth's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 222: Xerion's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 223: Xoma's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 224: Yakult Honsha's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 225: YM BioSciences' Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 226: Zivena's Included Lung Cancer Pipeline Composition and Competitive Fall-Out
    Table 227: Non-industrial source's Included Lung Cancer Pipeline Composition and Competitive Fall-Out