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Biotechnology

Handbook of Genome Research

Genomics, Proteomics, Metabolomics, Bioinformatics, Ethical and Legal Issues, Two Volumes

Publication Date   June 2005
Publisher   Wiley
Product Type   Book
Pages   646
ISBN Number   3-527-31348-6
Product Code   WIL015
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Price £175.00

approximately: $309 | €222

Summary


In this unique presentation of a revolutionary field of science, the first section introduces the domains of application for genomics and bioinformatics, such as sequencing and the comparative sequence analysis of model organisms, investigating genetically influenced diseases, the development of new active substances, agri-food and environmental genomics.

There then follows an overview of current topics central to DNA technologies, proteomics, metabolomics and bioinformatics, including such hot topics as DNA chip fabrication, yeast two hybrid analysis, tools for gene expression studies, metabolic networks and systems biology.

The whole is rounded off by four chapters on the ethical, legal and social aspects of this sensitive topic.

Content


I Key Organisms

Genome Projects on Model Organisms
Environmental Genomics: A Novel Tool for Study of Uncultivated Microorganisms
Applications of Genomics in Plant Biology

II Genomic And Proteomic Technologies

Human Genetic Diseases
Genomic Mapping and Positional Cloning, with Emphasis on Plant Science
DNA Sequencing Technology
Proteomics and Mass Spectrometry for the Biological Researcher
Proteome Analysis by Capillary Electrophoresis
A DNA Microarray Fabrication Strategy for Research Laboratories
Principles of Application of DNA Microarrays
Yeast Two-hybrid Technologies
Structural Genomics

III Bioinformatics

Bioinformatics Tools for DNA Technology
Software Tools for Proteomics Technologies
Applied Bioinformatics for Drug Discovery and Development
Genome Data Representation Through Images: The MAGPIE/Bluejay System
Bioinformatics Tools for Gene-expression Studies
Protein Interaction Databases
Bioinformatics Approaches for Metabolic Pathways
Systems Biology

IV Ethical, Legal And Social Issues

Ethical Aspects of Genome Research and Banking
Biobanks and the Challenges of Commercialization
The (Im)perfect Human -
His Own Creator? Bioethics and Genetics at the Beginning of Life

V Outlook

The Future of Large-Scale Life Science Research